West, who has been campaigning against the stigmatisation of people with mental health issues, opened up in the new season of David Letterman’s Netflix show, “My Next Guest Needs No Introduction.”

In a clip of the episode, which is set to drop Friday, Letterman asks West, “What is the mechanism that is malfunctioning or is taking a break in your brain, do you know?”

West replied, “I wouldn’t be able to explain that as much just because, you know, I’m not a doctor.

“I can just tell you what I’m feeling at the time, and I feel a heightened connection with the universe when I’m ramping up. It is a health issue.

Kim Kardashian and Kanye West have  [Instagram/KimKardashianWest]
Kardashian and Kanye West
Kim 

“This — it’s like a sprained brain, like having a sprained ankle. And if someone has a sprained ankle, you’re not going to push on him more.

“With us, once our brain gets to a point of spraining, people do everything to make it worse.

“You have this moment [where] you feel everyone wants to kill you. You pretty much don’t trust anyone.